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Found 3 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2' and Ligand = 'BDBM154576'
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM154576(K03861 (1))
Affinity DataIC50: >1.00E+4nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM154576(K03861 (1))
Affinity DataKd:  53nMAssay Description:Binding affinity to wild-type CDK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM154576(K03861 (1))
Affinity DataKd:  50nMpH: 7.5 T: 2°CAssay Description:All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 °C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...More data for this Ligand-Target Pair