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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome b-245 heavy chain' and Ligand = 'BDBM50497268'
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed