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Found 7 Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM364218'
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM364218(US9856263, 1 | US9856263, 2 | US9856263, 3)
Affinity DataKi:  4.5nMAssay Description:Frozen cells were quickly thawed, re-suspended in 50 mL warm media and allowed to sit for 5 min prior to centrifugation (1000 rpm) at room temperatur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM364218(US9856263, 1 | US9856263, 2 | US9856263, 3)
Affinity DataKi:  5.5nMAssay Description:Frozen cells were quickly thawed, re-suspended in 50 mL warm media and allowed to sit for 5 min prior to centrifugation (1000 rpm) at room temperatur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM364218(US9856263, 1 | US9856263, 2 | US9856263, 3)
Affinity DataKi:  20.5nMAssay Description:Frozen cells were quickly thawed, re-suspended in 50 mL warm media and allowed to sit for 5 min prior to centrifugation (1000 rpm) at room temperatur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM364218(US9856263, 1 | US9856263, 2 | US9856263, 3)
Affinity DataEC50:  0.871nMAssay Description:Agonist activity at recombinant human D1 receptor expressed in HEK29T cells assessed as induction of stimulatory G-protein-mediated cAMP accumulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM364218(US9856263, 1 | US9856263, 2 | US9856263, 3)
Affinity DataEC50:  0.870nMAssay Description:Agonist activity at recombinant human D1 receptor expressed in HEK29T cells assessed as induction of stimulatory G-protein-mediated cAMP accumulation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM364218(US9856263, 1 | US9856263, 2 | US9856263, 3)
Affinity DataEC50:  692nMAssay Description:Agonist activity at recombinant C-terminal RLuc8-fused human D1 receptor expressed in HEK29T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM364218(US9856263, 1 | US9856263, 2 | US9856263, 3)
Affinity DataEC50:  690nMAssay Description:Agonist activity at recombinant C-terminal RLuc8-fused human D1 receptor expressed in HEK29T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed