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Found 16 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50060601'
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  0.0400nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p (Pre treated with 1 uM) calculated for the high affinity components of the [3H]spiroperidol b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  0.0400nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  0.0600nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  0.0900nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  0.0900nMAssay Description:Inhibitory constant of compound in absence of Gpp(NH)p calculated for the high affinity components of the [3H]spiroperidol binding to Dopamine recept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  0.130nMAssay Description:Inhibitor constant of compound for high affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  0.130nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p calculated for the high affinity components of the [3H]spiroperidol binding to Dopamine recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  60nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  60nMAssay Description:Inhibitory constant of compound in absence of Gpp(NH)p (Pre treated with 1 uM) calculated for the high affinity components of the [3H]spiroperidol bi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  60nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  60nMAssay Description:Inhibitory constant of compound in presence of Gpp(NH)p calculated for the low affinity components of the [3H]spiroperidol binding to Dopamine recept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  60.1nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  73nMAssay Description:Inhibitory constant of compound in absence of Gpp(NH)p calculated for the low affinity components of the [3H]spiroperidol binding to Dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  73.2nMAssay Description:Inhibitor constant of compound for low affinity component of [3H]-spiroperidol/N-propylnorapomorphine binding to Dopamine receptor D2 in absence of G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataKi:  78nMAssay Description:Percentage of receptor in the high affinity form for the compound to Dopamine receptor D2 in absence of Gpp(NH)p (pre treated with 1 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50060601((E)-6-(3-oxo-3-phenylprop-1-enyl)pyrimidine-2,4(1H...)
Affinity DataEC50:  170nMAssay Description:Inhibition of PIM in human MV4-11 cells assessed as Akt phosphorylation at Ser473 measured after over night incubation by lotting based cellular assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed