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Found 7 Enz. Inhib. hit(s) with Target = 'DNA repair protein RAD51 homolog 1' and Ligand = 'BDBM48804'
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human RAD51More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataIC50:  2.74E+4nMAssay Description:Inhibition of human RAD51 using 90-mer ssDNA as substrate measured after 30 mins by D-loop assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human RAD51-mediated DNA strand exchange at using pBSK (+) gapped and linear dsDNA substrates by joint molecule formation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human RAD51-mediated DNA branch migration using [32P]-labeled 5'-joint molecules after 8 hrs by branch migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataIC50:  3.70E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataIC50:  4.25E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataKd:  5.60E+3nMAssay Description:Binding affinity to human RAD51 in absence of ATP by SPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed