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Found 3 Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase subunit alpha' and Ligand = 'BDBM466508'
TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli K-12)
TBA

US Patent
LigandPNGBDBM466508(US10800725, Compound 16)
Affinity DataIC50: >4.00E+5nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466508(US10800725, Compound 16)
Affinity DataIC50: >4.00E+5nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM466508(US10800725, Compound 16)
Affinity DataIC50: >4.00E+5nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent