Found 3 Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase subunit alpha' and Ligand = 'BDBM466525'
Affinity DataIC50: 1.40E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair