Compile Data Set for Download or QSAR
maximum 50k data
Found 1 Enz. Inhib. hit(s) with Target = 'Delta(24)-sterol reductase' and Ligand = 'BDBM20186'
TargetDelta(24)-sterol reductase(Homo sapiens)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM20186((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed