Found 7 Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 3' and Ligand = 'BDBM50179360' TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of recombinant human NPP3 expressed in CHO cells using ATP as substrate measured after 20 mins by mini-capillary electrophoresisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of human NPP3 transfected in COS7 cells using pNP-TMP as substrate incubated for 35 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant NPP3 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human recombinant N-terminal His6 tagged NPP3 expressed in baculovirus infected Sf9 cell membranes using pNP-TMP as substrate preincuba...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human NPP3 expressed in COS7 cells using p-nitrophenyl-5'-thymidine monophosphate as substrate preincubated for 5 to 10 mins followed b...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human full length NPP3 expressed in African green monkey COS7 cell membrane fraction using p-nitrophenyl-5'-thymidine monophosphate as ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
University Of Bonn
Curated by ChEMBL
University Of Bonn
Curated by ChEMBL
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair
