Affinity DataIC50: 0.200nMAssay Description:Inhibition of EphB4 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of EPHB4 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of EphB4 (unknown origin) after 1 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of EphB4 (unknown origin) after 4 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligandMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:Binding constant for EPHB4 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:Binding affinity to EPHB4More data for this Ligand-Target Pair
Affinity DataKd: 3.90E+3nMAssay Description:Average Binding Constant for EPHB4; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:Binding constant for EPHB4 kinase domainMore data for this Ligand-Target Pair