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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E (eIF4E)' and Ligand = 'BDBM50370489'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic translation initiation factor 4E (eIF4E)


(Homo sapiens (Human))
BDBM50370489
PNG
(CHEMBL607902)
Show SMILES CN1CN(C2O[C@H](CO)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=S)c12
Show InChI InChI=1S/C11H17N5O4S/c1-15-3-16(8-5(15)9(21)14-11(12)13-8)10-7(19)6(18)4(2-17)20-10/h4,6-7,10,17-19H,2-3H2,1H3,(H3,12,13,14,21)/t4-,6-,7-,10?/m1/s1
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Similars

Article
PubMed
n/an/a>4.00E+5n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E


Bioorg Med Chem Lett 15: 2177-80 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.080
BindingDB Entry DOI: 10.7270/Q27D2VWP
More data for this
Ligand-Target Pair