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Found 4 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50065306'
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL
LigandPNGBDBM50065306(3-[4-(1-formylpiperazin-4-yl)benzylidenyl]-2-indol...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of FGFR1K (unknown origin) autophosphorylation activity assessed as [32P] incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL
LigandPNGBDBM50065306(3-[4-(1-formylpiperazin-4-yl)benzylidenyl]-2-indol...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of FGFR1 kinase domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Mus musculus)
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50065306(3-[4-(1-formylpiperazin-4-yl)benzylidenyl]-2-indol...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of FGF induced FGFR1 autophosphorylation in mouse NIH 3T3 cells preincubated for 5 mins followed by FGF-stimulation for 5 mins in presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Mus musculus)
The First Affiliated Hospital Of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50065306(3-[4-(1-formylpiperazin-4-yl)benzylidenyl]-2-indol...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of acidic FGF-stimulated FGFR1 tyrosine autophosphorylation in mouse NIH/3T3 cells by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed