Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50514378'
TargetGTPase KRas(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50514378(CHEMBL4450657)
Affinity DataIC50:  44nMAssay Description:Inhibition of KRAS in human MIAPaca2 cells assessed as decrease in EGF-stimulated ERK1/2 phosphorylation preincubated for 2 hrs followed by EGF stimu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50514378(CHEMBL4450657)
Affinity DataIC50:  51nMAssay Description:Inhibition of GDP bound recombinant human His-tagged KRAS G12C/C118A mutant (1 to 169 residues) assessed as reduction in SOS1-mediated GDP/GTP nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed