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Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50527059'
TargetGTPase KRas(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50527059(CHEMBL4452974)
Affinity DataIC50:  18nMAssay Description:Inhibition of GDP bound biotinylated human C-terminal Avi/His6-tagged KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed