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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM485968'
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Cocrystal Pharma

US Patent
LigandPNGBDBM485968(US10947210, Compound 02-10E)
Affinity DataIC50: >1.00E+3nMAssay Description:The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Cocrystal Pharma

US Patent
LigandPNGBDBM485968(US10947210, Compound 02-10E)
Affinity DataEC50:  550nMAssay Description:HCV replicon assay is based on the luciferase reporter cell line (Huh-luc/neo-ET). This reporter cell line is a human liver carcinoma cell line (Huh-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent