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Found 8 Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50098571'
TargetGlucagon receptor(Rattus norvegicus)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro receptor binding affinity (95% CL) using rat liver plasma membrane bioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataIC50:  1.5nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataIC50:  1.5nMAssay Description:inhibition of [125]glucagon specific binding.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataIC50:  1.5nMAssay Description:Compound was tested for its ability to displace [I-125]-glucagon from the glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlucagon receptor(Rattus norvegicus)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataEC50:  5nMAssay Description:In vitro receptor binding affinity (95% CL) using rat liver plasma membrane bioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataEC50:  0.0710nMAssay Description:Agonist activity at GCGR expressed in HEK293 cells assessed as stimulation of cAMP production by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50098571(CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-...)
Affinity DataEC50:  8nMAssay Description:cAMP accumulation in rat hepatocytes in the presence rolipramMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed