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Found 6 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50318300'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataKi:  3.16E+3nMAssay Description:Binding affinity to recombinant human GR LBD by fluormone GS red-fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50: >8.94E+3nMAssay Description:Antagonist activity at glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]dexomethasone from GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50:  1.80E+4nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by NH Pro assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataIC50:  5.38E+4nMAssay Description:Displacement of [3H]-dexamethasone from recombinant full length human glucocorticoid receptor expressed in baculovirus infected insect cells incubate...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) by NH Pro assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed