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Found 3 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha' and Ligand = 'BDBM50464552'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50464552(CHEMBL4291855 | US10464907, Compound 14g | US10889...)
Affinity DataIC50:  429nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50464552(CHEMBL4291855 | US10464907, Compound 14g | US10889...)
Affinity DataIC50:  429nMAssay Description:Endonuclease activity assays were carried out in Black Costar 96-well plates. Each well contained a total volume of 100 μL comprised of: buffer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Bovine)
Industry Academic Cooperation Foundation Keimyung University

US Patent
LigandPNGBDBM50464552(CHEMBL4291855 | US10464907, Compound 14g | US10889...)
Affinity DataIC50:  429nMAssay Description:Fluorescence polarization assay was performed to confirm the binding ability to the compound synthesized with HSP90 according the concentration. 1 M ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent