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Found 8 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50247962'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  20nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  23nMAssay Description:Inhibition of GST-fused recombinant c-Met (unknown origin) catalytic domain expressed in baculovirus-infected Trichoplusia ni Hi5 cells after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  23nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  80nMAssay Description:Inhibition of c-Met-mediated scattering in HGF-stimulated human DU145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  80nMAssay Description:Inhibition of c-Met-mediated cell migration of human A549 cells by would healingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  120nMAssay Description:Inhibition of TPR-fused Met (unknown origin) phosphorylation expressed in human 293T cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed