Found 11 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM2579'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of TRKA (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant His-tagged human TrKA expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: <1.00E+6nMAssay Description:Inhibition of human Trk-A using myelin basic protein as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Binding constant for TRKA kinase domainMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Average Binding Constant for NTRK1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Binding constant for TRKA kinase domainMore data for this Ligand-Target Pair