Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3' and Ligand = 'BDBM476623' TargetHistone deacetylase 3(Homo sapiens (Human))
Medical University Of South Carolina
Curated by ChEMBL
Medical University Of South Carolina
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Allosteric inhibition of C-terminal His-tagged recombinant human HDAC3 expressed in Sf9 cells pre-incubated for 2 hrs before acetylated lysine-aminom...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Medical University Of South Carolina
Curated by ChEMBL
Medical University Of South Carolina
Curated by ChEMBL
Affinity DataIC50: 84.4nMAssay Description:Recombinant HDACs 1, 2, and 3 (BPS Biosciences) were diluted to a concentration of 1 nM in HDAC buffer. 10 uL of this solution was added in 96-well f...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Medical University Of South Carolina
Curated by ChEMBL
Medical University Of South Carolina
Curated by ChEMBL
Affinity DataIC50: 1.88E+3nMAssay Description:Allosteric inhibition of HDAC3 in HEK293 cell lysates pre-incubated for 2 hrs before acetylated lysine-aminomethyl coumarin-BOC addition and measured...More data for this Ligand-Target Pair
