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Found 3 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM50400778'
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50400778(CHEMBL2204995)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50400778(CHEMBL2204995)
Affinity DataIC50:  174nMAssay Description:Inhibition of EZH2-mediated proliferation of human LNCaP cells after 6 days by chemiluminescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50400778(CHEMBL2204995)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of EZH2-mediated proliferation of human LNCaP cells after 6 days by chemiluminescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed