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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase MLL2' and Ligand = 'BDBM50508569'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone-lysine N-methyltransferase MLL2


(Homo sapiens (Human))
BDBM50508569
PNG
(CHEMBL4557353)
Show SMILES CCCCOc1ccc(cc1C)S(=O)(=O)Nc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C18H21NO5S/c1-3-4-11-24-17-10-9-16(12-13(17)2)25(22,23)19-15-7-5-14(6-8-15)18(20)21/h5-10,12,19H,3-4,11H2,1-2H3,(H,20,21)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Zhejiang Sci-Tech University

Curated by ChEMBL


Assay Description
Inhibition of MLL2 (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alphali...


Bioorg Med Chem Lett 29: 638-645 (2019)


Article DOI: 10.1016/j.bmcl.2018.12.035
More data for this
Ligand-Target Pair