Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Integrase' and Ligand = 'BDBM107693'
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)
Affinity DataIC50:  80nMAssay Description:Inhibition of HIV integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)
Affinity DataIC50:  400nMAssay Description:Inhibition of HIV1 recombinant integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)
Affinity DataIC50:  520nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)
Affinity DataIC50:  520nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed