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Found 2 Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM107742'
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM107742(US8933095, 26)
Affinity DataIC50:  40.7nMT: 2°CAssay Description:Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM107742(US8933095, 26)
Affinity DataIC50:  40.7nMAssay Description:Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...More data for this Ligand-Target Pair
In DepthDetails US Patent