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Found 6 Enz. Inhib. hit(s) with Target = 'Kynurenine 3-monooxygenase' and Ligand = 'BDBM50061915'
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataKi:  95nMAssay Description:Inhibitory constant of the compound against Kynurenine 3-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  200nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat KMOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  237nMAssay Description:Inhibition of rat kidney Kynurenine 3-hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  330nMAssay Description:Compound was evaluated for the inhibition of rat liver KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed