Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Large neutral amino acids transporter small subunit 1' and Ligand = 'BDBM18140'
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18140((2S,3S)-2-amino-3-methylpentanoic acid | Isoleucin...)
Affinity DataIC50:  1.40E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18140((2S,3S)-2-amino-3-methylpentanoic acid | Isoleucin...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human LAT1 expressed in HEK293-T-Rex cells assessed as inhibition of [3H]-gabapentin uptake by scintillation counting cis-inhibition as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed