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Found
1
Enz. Inhib. hit(s) with Target = 'Leukotriene C4 synthase' and Ligand = 'BDBM310035'
Target
Leukotriene C4 synthase
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM310035
((1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(propy...)
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Affinity Data
IC50: 0.483nM
Assay Description:
In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...
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Target Info
PDB
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Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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Ligand Info
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In Depth
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US Patent
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