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Found 2 Enz. Inhib. hit(s) with Target = 'Leukotriene C4 synthase' and Ligand = 'BDBM50519591'
TargetLeukotriene C4 synthase(Homo sapiens (Human))
Orexo

Curated by ChEMBL
LigandPNGBDBM50519591(CHEMBL4562583)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human N-terminal His6-tagged LTC4S expressed in Pichia pastoris X33 using LTA4 methyl ester and glutathione as substrate preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene C4 synthase(Homo sapiens (Human))
Orexo

Curated by ChEMBL
LigandPNGBDBM50519591(CHEMBL4562583)
Affinity DataIC50:  16nMAssay Description:Inhibition of LTC4S in zymosan-stimulated human PBMC assessed as inhibition of LTC4 production preincubated for 45 mins followed by zymosan stimulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed