Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMpH: 7.5Assay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:Competition binding experiments were conducted by incubating membrane protein to equilibrium in triplicate in the presence of a fixed concentration o...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair