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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50313639'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50313639
PNG
(1-(4-(1-methyl-1H-pyrazol-4-yl)benzyl)indoline-2,3...)
Show SMILES Cn1cc(cn1)-c1ccc(CN2C(=O)C(=O)c3ccccc23)cc1
Show InChI InChI=1S/C19H15N3O2/c1-21-12-15(10-20-21)14-8-6-13(7-9-14)11-22-17-5-3-2-4-16(17)18(23)19(22)24/h2-10,12H,11H2,1H3
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PC cid
PC sid
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Similars

PCBioAssay
n/an/an/an/a 2.71E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Selective M1 activation is an attractive therapeutic approach for the treatment of cognitive impairment, Alzheimer's disease, schizophrenia and a...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q22V2DJR
More data for this
Ligand-Target Pair