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Found 8 Enz. Inhib. hit(s) with Target = 'N-lysine methyltransferase SMYD2' and Ligand = 'BDBM50519300'
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human U2OS cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in HEK293 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methylati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human MDA-MB-231 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human HeLa cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human CAL120 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human MCF7 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB