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Found 5 Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50073120'
TargetNeprilysin(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataKi:  9nMAssay Description:Inhibition of human somatic NEPMore data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  8nMAssay Description:Inhibition of rat kidney NEP using dansyl-Gly-Phe-Arg as substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against purified rat kidney neutral endopeptidase (NEP) using a fluorometric assay with dansyl-Gly-Phe-Arg as the substr...More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair