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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50336404'
LigandPNGBDBM50336404(4-amino-2,6-dimethyl-N-(1H-pyrazol-5-yl)quinazolin...)
Affinity DataKi:  7nMAssay Description:Inhibition of PI3Kalpha by fluorescene polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50336404(4-amino-2,6-dimethyl-N-(1H-pyrazol-5-yl)quinazolin...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PI3Kalpha-phosphorylation at S473 residue in human BT20 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed