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Found 8 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM394289'
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50: <50nMAssay Description:Assay A2: The kinase reaction was conducted in clear-bottom 96-well plate from Thermo Fisher Scientific in a final volume of 24 μL. Inhibitors w...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50: <50nMAssay Description:Example A3: The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50: <50nMAssay Description:PI3Kα, PI3Kβ, PI3Kγ: The kinase reaction was conducted in clear-bottom 96-well plate from Thermo Fisher Scientific in a final volume o...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50: <50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50:  75nMAssay Description:Assay A1 PI3Kδ: The kinase reaction was conducted in 384-well REMP plate from Thermo Fisher Scientific in a final volume of 40 μL. Inhibito...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50:  75nMAssay Description:Assay A1: The kinase reaction was conducted in 384-well REMP plate from Thermo Fisher Scientific in a final volume of 40 μL. Inhibitors were fir...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50:  75nMAssay Description:Example A1: The kinase reaction was conducted in 384-well REMP plate from Thermo Fisher Scientific in a final volume of 40 μL. Inhibitors were f...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394289(US10428087, Example 8 | US10829502, Example 8 | US...)
Affinity DataIC50:  75nMAssay Description:PI3-Kinase luminescent assay kit including lipid kinase substrate, D-myo-phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2)D (+)-sn-1,2-di-O-octan...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent