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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50239117'
LigandPNGBDBM50239117(CHEMBL4060768)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of recombinant human PI3Kdelta using PIP2 as substrate preincubated for 20 mins followed by substrate addition measured after 80 mins in p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50239117(CHEMBL4060768)
Affinity DataIC50:  14nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 B cells assessed as decrease in AKT phosphorylation at Ser473 measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed