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Found 8 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM394294'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50:  300nMAssay Description:PI3Kδ Assay A3: The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50:  300nMAssay Description:Assay A3: The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50:  300nMAssay Description:Example A2: The kinase reaction was conducted in clear-bottom 96-well plate from Thermo Fisher Scientific in a final volume of 24 μL. Inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50:  300nMAssay Description:Materials: Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), was purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50: >500nMAssay Description:Example A2: The kinase reaction was conducted in clear-bottom 96-well plate from Thermo Fisher Scientific in a final volume of 24 μL. Inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50: >500nMAssay Description:PI3Kδ Assay A3: The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50: >500nMAssay Description:Materials: Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), was purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM394294(US10428087, Example 23 | US10829502, Example 23 | ...)
Affinity DataIC50: >500nMAssay Description:Assay A3: The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent