Found 14 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha' and Ligand = 'BDBM13530' TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 2nMAssay Description:Inhibition of PDGFRA (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 18nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 71nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 72nMAssay Description:Inhibition of human PDGFRalpha autophosphorylation in human A31 cells by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 96nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 160nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into polyAlaGluLsTyr after 60 mins by microplate scintillation count...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 642nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 642nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataKd: 31nMAssay Description:Binding constant for PDGFRA kinase domainMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataEC50: 90nMAssay Description:Inhibition of PDGFRalpha by cellular assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataKd: 31nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute Of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataKd: 31nMAssay Description:Binding constant for PDGFRA kinase domainMore data for this Ligand-Target Pair
