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Found 3 Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50126158'
TargetProgesterone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataIC50:  7.43nMAssay Description:Inhibitory progestational activity on oral administration in uterine C3 modelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataIC50:  16nMAssay Description:Inhibition of 3 nM [3H]-R5020 binding to progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataEC50:  0.360nMAssay Description:Effective concentration of progesterone receptor agonist induction of alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed