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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50333737'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataKi:  17nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333737(3-(4-(2-(2-(2-methoxyphenyl)acetamido)ethyl)phenyl...)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells by cell-based functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed