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Found 3 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM31523'
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Georgia

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataIC50:  5.00E+3nMAssay Description:Emulating Ratia et al., who detailed the potency of these four compounds against SARS-CoV-1, we utilized the peptide-AMC substrate concentration of 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Georgia

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of N-terminal His/TEV-tagged SARS-CoV-2 papain-like protease nsp3 (746 to 1060 residues) expressed in Escherichia coli BL21 (DE3) using (Z...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Georgia

LigandPNGBDBM31523(Compound 6 | Naphthalene and Benzamide Derivative,...)
Affinity DataEC50:  2.10E+4nMAssay Description:Emulating Ratia et al., who detailed the potency of these four compounds against SARS-CoV-1, we utilized the peptide-AMC substrate concentration of 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed