Found 5 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM419120' TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Michigan State University
Affinity DataKi: 9.00E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nMAssay Description:Binding affinity to SARS CoV-2 main protease pH41A mutant expressed in Escherichia coli BL21 DE3 cells using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substra...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Michigan State University
Affinity DataIC50: 9.00E+3nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+5nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.68E+4nMAssay Description:To further substantiate the enzymatic inhibition results in vitro, we evaluated whether these compounds could prevent viral replication in cell-based...More data for this Ligand-Target Pair
