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Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM420331'
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420331(AMG-837)
Affinity DataIC50:  2.42E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes Of Health

LigandPNGBDBM420331(AMG-837)
Affinity DataEC50:  1.12E+4nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed