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Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM448371'
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448371(Perampanel, 23)
Affinity DataIC50:  20nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448371(Perampanel, 23)
Affinity DataEC50:  840nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article