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Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM50197349'
TargetReplicase polyprotein 1ab(2019-nCoV)
University Ofamsterdam

LigandPNGBDBM50197349(CHEMBL3983492 | ebselen derivative 1e)
Affinity DataIC50:  256nMAssay Description:The inhibitor was screened against recombinant PL​pro​SARS and PL​pro​CoV2 at 37°Cin the assay buffer as described above. For...More data for this Ligand-Target Pair
In DepthDetails
TargetReplicase polyprotein 1ab(2019-nCoV)
University Ofamsterdam

LigandPNGBDBM50197349(CHEMBL3983492 | ebselen derivative 1e)
Affinity DataIC50:  256nMAssay Description:Inhibition of SARS-CoV-2 PLproMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Ofamsterdam

LigandPNGBDBM50197349(CHEMBL3983492 | ebselen derivative 1e)
Affinity DataIC50:  256nMAssay Description:Inhibition of SARS-CoV-2 papain-like protease preincubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Ofamsterdam

LigandPNGBDBM50197349(CHEMBL3983492 | ebselen derivative 1e)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant SARS CoV-2 PL protease incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed