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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta' and Ligand = 'BDBM50048291'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta


(Homo sapiens (Human))
BDBM50048291
PNG
(6-(3-Adamantan-1-yl-4-hydroxy-phenyl)-naphthalene-...)
Show SMILES OC(=O)c1ccc2cc(ccc2c1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
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Similars

Article
PubMed
n/an/an/an/a 226n/an/an/an/a



Nestle Skin Health

Curated by ChEMBL


Assay Description
Agonist activity at GAL4 DNA-binding domain-tagged RARbeta (unknown origin) ligand-binding domain expressed in human HG5LN cells incubated for 18 hrs...


Bioorg Med Chem Lett 28: 1736-1741 (2018)


Article DOI: 10.1016/j.bmcl.2018.04.036
BindingDB Entry DOI: 10.7270/Q2N300JQ
More data for this
Ligand-Target Pair