Found 50 Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor alpha' and Ligand = 'BDBM31883' 
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards human Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-alphaMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 187nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Binding affinity for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of murine Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of binding to retinoid A receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]-ATRA binding to mouse Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Binding affinity against retinoic Acid alpha receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding affinity for baculovirus-expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Apparent binding constant against Retinoic acid receptor alpha in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 459nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 15nMAssay Description:Dissociation constant for binding to Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity fo retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from alpha retinoic acid receptor (alpha RAR) using transactivation assayMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]-ATRA binding to human Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Activity at human RARalpha ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 ...More data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Agonist activity for retinoic acid receptor RAR alpha in transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Transcriptional activation of retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Compound was tested for binding affinity against retinoic acid receptor using 5 nM of [3H]-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Activation of RXRalpha (unknown origin) by CAT reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.31nMAssay Description:Activity at RARalpha expressed in mouse NIH3T3 cells by R-SAT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]-9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 436nMAssay Description:Transcriptional activation in CV-1 cells expresing human Retinoid X receptor RXR-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Ability to inhibit TTNPB-induced transactivation at retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Transactivation of mouse Gal4-fused RARalpha-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Transactivation of human Gal4-DBD-fused RARalpha-LBD expressed in HEK293T cells after 16 to 24 hrs by FRET based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Transactivation of GST-tagged RARalpha LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by ...More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity RARalpha (unknown origin) assessed as induction of receptor transactivationMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:Transactivation of GAL4-fused mouse RARalpha-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Binding affinity against retinoic Acid alpha receptors cotransfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 563nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Ability to inhibit TTNPB-induced transactivation at retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Effective concentration for retinoic acid receptor RAR alpha transcriptional activationMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity RARalpha (unknown origin) assessed as induction of receptor transactivationMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding affinity for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
