TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <0.169nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <0.169nMpH: 7.5 T: 2°CAssay Description:TR-FRET assay for retinol-induced RBP4-TTR interaction Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR inte...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <1.37nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <1.37nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <1.37nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <1.37nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <1.37nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: <1.37nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 5.12nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 5.12nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 5.12nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 5.12nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 5.12nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 5.12nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 7.41nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York
US Patent
The Trustees Of Columbia University In The City Of New York
US Patent
Affinity DataIC50: 7.41nMpH: 7.5 T: 2°CAssay Description:TR-FRET assay for retinol-induced RBP4-TTR interaction Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR inte...More data for this Ligand-Target Pair