Found 9 Enz. Inhib. hit(s) with Target = 'Retinol-binding protein 4' and Ligand = 'BDBM249559' TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Competitive displacement of 3[H]retinol from biotinylated RBP4 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 5.84nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 5.84nMAssay Description:The analogs of Compounds 63-162 described herein analogously bind to RBP4 and antagonize retinol-dependent RBP4-TTR interaction. Additional piperidin...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 5.84nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 5.84nMpH: 7.5Assay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7)...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 5.84nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 5.84nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR interaction resulting in the decreased FRET signal (FIG. 7 ...More data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Albany College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataIC50: 92.0nMpH: 7.5 T: 2°CAssay Description:TR-FRET assay for retinol-induced RBP4-TTR interaction Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR inte...More data for this Ligand-Target Pair
