Found 13 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM14029'
Affinity DataKi: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 150nM ΔG°: -39.6kJ/molepH: 7.6 T: 2°CAssay Description:The enzyme activity was assayed by using an ATP regenerative NADH consuming system. The reaction was started with adding ATP to the mixture containin...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of human leukocytic ROCK1 expressed in insect cells using KKRNRTLSV as substrate after 10 mins by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of human ROCK1 by homogenous luciferase assayMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of ROCK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant N-terminal his-tagged ROCK1 (3-543) expressed in baculovirus infected Sf9 cells using Biotin-Ahx-AKRRLSSLRA-CONH2 sub...More data for this Ligand-Target Pair
Affinity DataIC50: 871nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair